Renal Accumulation of Biglycan and Lipid Retention Accelerates Diabetic Nephropathy

Hyperlipidemia worsens diabetic nephropathy, although the mechanism by which renal lipids accumulate is unknown. We previously demonstrated that renal proteoglycans have high low-density lipoprotein (LDL) binding affinity, suggesting that proteoglycan-mediated LDL retention may contribute to renal l...

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Detalhes bibliográficos
Main Authors: Thompson, Joel, Wilson, Patricia, Brandewie, Katie, Taneja, Deepa, Schaefer, Liliana, Mitchell, Bonnie, Tannock, Lisa R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157166/
https://ncbi.nlm.nih.gov/pubmed/21723246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.05.016
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