Methylation QTLs Are Associated with Coordinated Changes in Transcription Factor Binding, Histone Modifications, and Gene Expression Levels

DNA methylation is an important epigenetic regulator of gene expression. Recent studies have revealed widespread associations between genetic variation and methylation levels. However, the mechanistic links between genetic variation and methylation remain unclear. To begin addressing this gap, we co...

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Autors principals: Banovich, Nicholas E., Lan, Xun, McVicker, Graham, van de Geijn, Bryce, Degner, Jacob F., Blischak, John D., Roux, Julien, Pritchard, Jonathan K., Gilad, Yoav
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169251/
https://ncbi.nlm.nih.gov/pubmed/25233095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004663
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