Methylation QTLs Are Associated with Coordinated Changes in Transcription Factor Binding, Histone Modifications, and Gene Expression Levels

DNA methylation is an important epigenetic regulator of gene expression. Recent studies have revealed widespread associations between genetic variation and methylation levels. However, the mechanistic links between genetic variation and methylation remain unclear. To begin addressing this gap, we co...

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Main Authors: Banovich, Nicholas E., Lan, Xun, McVicker, Graham, van de Geijn, Bryce, Degner, Jacob F., Blischak, John D., Roux, Julien, Pritchard, Jonathan K., Gilad, Yoav
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169251/
https://ncbi.nlm.nih.gov/pubmed/25233095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004663
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