Methylation QTLs Are Associated with Coordinated Changes in Transcription Factor Binding, Histone Modifications, and Gene Expression Levels

DNA methylation is an important epigenetic regulator of gene expression. Recent studies have revealed widespread associations between genetic variation and methylation levels. However, the mechanistic links between genetic variation and methylation remain unclear. To begin addressing this gap, we co...

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Detalhes bibliográficos
Main Authors: Banovich, Nicholas E., Lan, Xun, McVicker, Graham, van de Geijn, Bryce, Degner, Jacob F., Blischak, John D., Roux, Julien, Pritchard, Jonathan K., Gilad, Yoav
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169251/
https://ncbi.nlm.nih.gov/pubmed/25233095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004663
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