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Designed BH3 Peptides with High Affinity and Specificity for Targeting Mcl-1 in Cells
[Image: see text] Mcl-1 is overexpressed in many cancers and can confer resistance to cell-death signaling in refractory disease. Molecules that specifically inhibit Mcl-1 hold potential for diagnosing and disrupting Mcl-1-dependent cell survival. We selected three peptides from a yeast-surface disp...
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| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical
Society
2014
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4168798/ https://ncbi.nlm.nih.gov/pubmed/25052212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500340w |
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