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Near-optimal assembly for shotgun sequencing with noisy reads

Recent work identified the fundamental limits on the information requirements in terms of read length and coverage depth required for successful de novo genome reconstruction from shotgun sequencing data, based on the idealistic assumption of no errors in the reads (noiseless reads). In this work, w...

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Sonraí Bibleagrafaíochta
Main Authors: Lam, Ka-Kit, Khalak, Asif, Tse, David
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168708/
https://ncbi.nlm.nih.gov/pubmed/25252708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-S9-S4
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