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Near-optimal assembly for shotgun sequencing with noisy reads

Recent work identified the fundamental limits on the information requirements in terms of read length and coverage depth required for successful de novo genome reconstruction from shotgun sequencing data, based on the idealistic assumption of no errors in the reads (noiseless reads). In this work, w...

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Autori principali: Lam, Ka-Kit, Khalak, Asif, Tse, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168708/
https://ncbi.nlm.nih.gov/pubmed/25252708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-S9-S4
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