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Near-optimal assembly for shotgun sequencing with noisy reads

Recent work identified the fundamental limits on the information requirements in terms of read length and coverage depth required for successful de novo genome reconstruction from shotgun sequencing data, based on the idealistic assumption of no errors in the reads (noiseless reads). In this work, w...

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Hlavní autoři: Lam, Ka-Kit, Khalak, Asif, Tse, David
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168708/
https://ncbi.nlm.nih.gov/pubmed/25252708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-S9-S4
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