Clinical Characteristics of Ovarian Cancer Classified by BRCA1, BRCA2, and RAD51C Status

We evaluated homologous recombination deficient (HRD) phenotypes in epithelial ovarian cancer (EOC) considering BRCA1, BRCA2, and RAD51C in a large well-annotated patient set. We evaluated EOC patients for germline deleterious mutations (n = 899), somatic mutations (n = 279) and epigenetic alteratio...

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Main Authors: Cunningham, J. M., Cicek, M. S., Larson, N. B., Davila, J., Wang, C., Larson, M. C., Song, H., Dicks, E. M., Harrington, P., Wick, M., Winterhoff, B. J., Hamidi, H., Konecny, G. E., Chien, J., Bibikova, M., Fan, J.-B., Kalli, K. R., Lindor, N. M., Fridley, B. L., Pharoah, P. P. D., Goode, E. L.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168524/
https://ncbi.nlm.nih.gov/pubmed/24504028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04026
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