Effect of mushroom diet on pharmacokinetics of gabapentin in healthy Chinese subjects

AIMS: This study evaluated the pharmacokinetics of gabapentin in Chinese subjects who received a diet rich in shiitake mushrooms. Shiitake mushrooms have been shown to contain high amount of ergothioneine. In vitro studies have shown that OCTN1-mediated secretion of gabapentin is trans-stimulated by...

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Detalhes bibliográficos
Main Authors: Toh, Dorothy Su Lin, Limenta, Lie Michael George, Yee, Jie Yin, Wang, Ling-Zhi, Goh, Boon-Cher, Murray, Michael, Lee, Edmund Jon Deoon
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Drug Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168387/
https://ncbi.nlm.nih.gov/pubmed/24168107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12273
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