First-in-Human Evaluation of a Hexon Chimeric Adenovirus Vector Expressing HIV-1 Env (IPCAVD 002)

Background. We report the first-in-human safety and immunogenicity assessment of a prototype hexon chimeric adenovirus (Ad) serotype 5 (Ad5) vector containing the hexon hypervariable regions of Ad serotype 48 (Ad48) and expressing human immunodeficiency virus (HIV) type 1 EnvA. Methods. Forty-eight...

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Bibliografiset tiedot
Päätekijät: Baden, Lindsey R., Walsh, Stephen R., Seaman, Michael S., Johnson, Jennifer A., Tucker, Robert P., Kleinjan, Jane A., Gothing, Jon A., Engelson, Brian A., Carey, Brittany R., Oza, Avinash, Bajimaya, Shringkhala, Peter, Lauren, Bleckwehl, Chelsea, Abbink, Peter, Pau, Maria G., Weijtens, Mo, Kunchai, Meghan, Swann, Edith M., Wolff, Mark, Dolin, Raphael, Barouch, Dan H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2014
Aiheet:
Major Articles and Brief Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168302/
https://ncbi.nlm.nih.gov/pubmed/24719474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu217
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