First-in-Human Evaluation of a Hexon Chimeric Adenovirus Vector Expressing HIV-1 Env (IPCAVD 002)

Background. We report the first-in-human safety and immunogenicity assessment of a prototype hexon chimeric adenovirus (Ad) serotype 5 (Ad5) vector containing the hexon hypervariable regions of Ad serotype 48 (Ad48) and expressing human immunodeficiency virus (HIV) type 1 EnvA. Methods. Forty-eight...

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Bibliografische gegevens
Hoofdauteurs: Baden, Lindsey R., Walsh, Stephen R., Seaman, Michael S., Johnson, Jennifer A., Tucker, Robert P., Kleinjan, Jane A., Gothing, Jon A., Engelson, Brian A., Carey, Brittany R., Oza, Avinash, Bajimaya, Shringkhala, Peter, Lauren, Bleckwehl, Chelsea, Abbink, Peter, Pau, Maria G., Weijtens, Mo, Kunchai, Meghan, Swann, Edith M., Wolff, Mark, Dolin, Raphael, Barouch, Dan H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
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Major Articles and Brief Reports
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168302/
https://ncbi.nlm.nih.gov/pubmed/24719474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu217
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