First-in-Human Evaluation of the Safety and Immunogenicity of a Recombinant Adenovirus Serotype 26 HIV-1 Env Vaccine (IPCAVD 001)

Background. We report the first-in-human safety and immunogenicity assessment of a prototype Ad26 vector-based human immunodeficiency virus (HIV) vaccine in humans. Methods. Sixty Ad26-seronegative, healthy, HIV-uninfected subjects were enrolled in a randomized, double-blinded, placebo-controlled, d...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Baden, Lindsey R., Walsh, Stephen R., Seaman, Michael S., Tucker, Robert P., Krause, Kathleen H., Patel, Alka, Johnson, Jennifer A., Kleinjan, Jane, Yanosick, Katherine E., Perry, James, Zablowsky, Elise, Abbink, Peter, Peter, Lauren, Iampietro, M. Justin, Cheung, Ann, Pau, Maria G., Weijtens, Mo, Goudsmit, Jaap, Swann, Edith, Wolff, Mark, Loblein, Hayley, Dolin, Raphael, Barouch, Dan H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2013
Aiheet:
Major Articles and Brief Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532831/
https://ncbi.nlm.nih.gov/pubmed/23125444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis670
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