Metabolic profiling of praziquantel enantiomers

Praziquantel (PZQ), prescribed as a racemic mixture, is the most readily available drug to treat schistosomiasis. In the present study, ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry (UPLC-ESI-QTOFMS) based metabolomics was em...

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Hoofdauteurs: Wang, Haina, Fang, Zhong-Ze, Zheng, Yang, Zhou, Kun, Hu, Changyan, Krausz, Kristopher W, Sun, Dequn, Idle, Jeffrey R., Gonzalez, Frank J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168258/
https://ncbi.nlm.nih.gov/pubmed/24821110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.05.001
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