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Validation of the VE1 Immunostain for the BRAF V600E Mutation in Melanoma

BACKGROUND: BRAF mutation status, and therefore eligibility for BRAF inhibitors, is currently determined by sequencing methods. We assessed the validity of VE1, a monoclonal antibody against the BRAF V600E mutant protein, in the detection of mutant BRAF V600E melanomas as classified by DNA pyroseque...

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Detalhes bibliográficos
Main Authors: Pearlstein, Michelle V., Zedek, Daniel C., Ollila, David W., Treece, Amanda, Gulley, Margaret L., Groben, Pamela A., Thomas, Nancy E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167935/
https://ncbi.nlm.nih.gov/pubmed/24917033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cup.12364
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