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Phase 2 Trial of Linifanib (ABT-869) in Patients with Advanced Renal Cell Cancer (RCC) after Sunitinib Failure

PURPOSE: This study assessed the efficacy and safety of linifanib in patients with advanced renal cell carcinoma (RCC) who were previously treated with sunitinib. MATERIALS AND METHODS: This open-label, multicenter, phase 2 trial of oral linifanib 0.25 mg/kg/day enrolled patients who had prior nephr...

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Detalhes bibliográficos
Main Authors: Tannir, Nizar M., Wong, Yu-Ning, Kollmannsberger, Christian K., Ernstoff, Marc S., Perry, David J., Appleman, Leonard J., Posadas, Edwin M., Cho, Daniel, Choueiri, Toni K., Coates, Andrew, Gupta, Neeraj, Pradhan, Rajendra, Qian, Jiang, Chen, Jihong, Scappaticci, Frank A., Ricker, Justin L., Carlson, Dawn M., Michaelson, M. Dror
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167844/
https://ncbi.nlm.nih.gov/pubmed/22078932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2011.09.002
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