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Intermittent hypercapnia enhances CO(2) responsiveness and overcomes serotonergic dysfunction

Serotonergic dysfunction compromises ventilatory chemosensitivity and may enhance vulnerability to pathologies such as the Sudden Infant Death Syndrome (SIDS). We have shown raphé contributions to central chemosensitivity involving serotonin (5-HT)-and γ-aminobutyric acid (GABA)-mediated mechanisms....

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Detalhes bibliográficos
Main Authors: Mosher, Bryan P., Taylor, Barbara E., Harris, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167740/
https://ncbi.nlm.nih.gov/pubmed/24874557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2014.05.005
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