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Neutralizing antibody to human rhinovirus 14 penetrates the receptor-binding canyon

The three-dimensional structure of intact human rhinovirus 14 (HRV-14) complexed with Fab fragments (Fab17-IA) from a strongly neutralizing antibody that binds bivalently to the virion(1,2) has been determined to 4.0 Å resolution by a combination of X-ray crystallography and cryo-electron microscopy...

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Bibliographic Details
Main Authors: Smith, Thomas J, Chase, Elaine S., Schmidt, Timothy J., Olson, Norman H., Baker, Timothy S.
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167671/
https://ncbi.nlm.nih.gov/pubmed/8848050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/383350a0
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