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Evidence for the direct involvement of the rhinovirus canyon in receptor binding.

Evidence is presented that indicates a deep crevice located on the surface of human rhinovirus type 14 is involved in virion attachment to cellular receptors. By using mutagenesis of an infectious cDNA clone, 11 mutants were created by single amino acid substitutions or insertions at positions 103,...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Colonno, R J, Condra, J H, Mizutani, S, Callahan, P L, Davies, M E, Murcko, M A
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281774/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2840661/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.15.5449
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