Conformational change in the floor of the human rhinovirus canyon blocks adsorption to HeLa cell receptors.

A series of eight antiviral compounds complexed with human rhinovirus 14 (HRV-14) were previously shown to displace segments of polypeptide chains in the floor of the "canyon" by as much as 0.45 nm in C-alpha positions from the native conformation (J. Badger, I. Minor, M. J. Kremer, M. A....

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Pevear, D C, Fancher, M J, Felock, P J, Rossmann, M G, Miller, M S, Diana, G, Treasurywala, A M, McKinlay, M A, Dutko, F J
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1989
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250615/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2539499/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.5.2002-2007.1989
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge