Conformational change in the floor of the human rhinovirus canyon blocks adsorption to HeLa cell receptors.

A series of eight antiviral compounds complexed with human rhinovirus 14 (HRV-14) were previously shown to displace segments of polypeptide chains in the floor of the "canyon" by as much as 0.45 nm in C-alpha positions from the native conformation (J. Badger, I. Minor, M. J. Kremer, M. A. Oliveira,...

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Dades bibliogràfiques

Publicat a:	J Virol
Autors principals:	Pevear, D C, Fancher, M J, Felock, P J, Rossmann, M G, Miller, M S, Diana, G, Treasurywala, A M, McKinlay, M A, Dutko, F J
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1989
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250615/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2539499/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.5.2002-2007.1989
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