Nanomicelle formulation modifies the pharmacokinetic profiles and cardiac toxicity of daunorubicin

BACKGROUND: Treatment with daunorubicin (DNR) in acute myeloid leukemia is moderately effective and associated with significant side effects, including cardiac toxicity. We recently developed a nanomicellar formulation of DNR that specifically targets acute myeloid leukemia stem cells. MATERIALS &am...

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Main Authors: Zhang, Hongyong, Li, Yuanpei, Lin, Tzu-yin, Xiao, Kai, Haddad, Ashraf S, Henderson, Paul T, Jonas, Brian A, Chen, Mingyi, Xiao, Wenwu, Liu, Ruiwu, Lam, Kit S, Pan, Chong-xian
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167557/
https://ncbi.nlm.nih.gov/pubmed/24628688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.14.44
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