Tumor Microenvironmental Changes Induced by the Sulfamate Carbonic Anhydrase IX Inhibitor S4 in a Laryngeal Tumor Model

BACKGROUND AND PURPOSE: Carbonic anhydrase IX (CAIX) plays a pivotal role in pH homeostasis, which is essential for tumor cell survival. We examined the effect of the CAIX inhibitor 4-(3′(3″,5″-dimethylphenyl)-ureido)phenyl sulfamate (S4) on the tumor microenvironment in a laryngeal tumor model by a...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Meijer, Tineke W. H., Bussink, Johan, Zatovicova, Miriam, Span, Paul N., Lok, Jasper, Supuran, Claudiu T., Kaanders, Johannes H. A. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167542/
https://ncbi.nlm.nih.gov/pubmed/25225880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108068
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares