HSV-sr39TK positron emission tomography and suicide gene elimination of human hematopoietic stem cells and their progeny in humanized mice

Engineering immunity against cancer by the adoptive transfer of hematopoietic stem cells (HSC) modified to express antigen-specific T-cell-receptors (TCR) or chimeric antigen receptors (CAR) generates a continual supply of effector T-cells, potentially providing superior anti-cancer efficacy compare...

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Bibliografiske detaljer
Main Authors: Gschweng, Eric H., McCracken, Melissa N., Kaufman, Michael L., Ho, Michelle, Hollis, Roger P., Wang, Xiaoyan, Saini, Navdeep, Koya, Richard C., Chodon, Thinle, Ribas, Antoni, Witte, Owen N., Kohn, Donald B.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167467/
https://ncbi.nlm.nih.gov/pubmed/25038231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0376
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