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A New Nucleoside Analogue with Potent Activity against Mutant sr39 Herpes Simplex Virus-1 (HSV-1) Thymidine Kinase (TK)

[Image: see text] Nucleoside analogues, such as penciclovir, ganciclovir, acyclovir, and their fluoro-substituted derivatives, have wide utility as antivirals. Among these analogues, FHBG ((18)F-Fluorohydroxybutylguanine) is a well-validated PET (positron emission tomography) probe for monitoring re...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Sundaram, G.S.M., Harpstrite, Scott E., Kao, Jeff Lung-Fa, Collins, Silvia D., Sharma, Vijay
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617231/
https://ncbi.nlm.nih.gov/pubmed/22765027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol300728a
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