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Semiautomated Radiosynthesis and Biological Evaluation of [(18)F]FEAU: A Novel PET Imaging Agent for HSV1-tk/sr39tk Reporter Gene Expression
2′-Deoxy-2′-[(18)F]fluoro-5-ethyl-1-β-d-arabinofuranosyluracil ([(18)F]FEAU) is a promising radiolabeled nucleoside designed to monitor Herpes Simplex Virus Type 1 thymidine kinase (HSV1-tk) reporter gene expression with positron emission tomography (PET). However, the challenging radiosynthesis cre...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4141558/ https://ncbi.nlm.nih.gov/pubmed/18157580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-007-0122-3 |
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