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Interictal spikes precede ictal discharges in an organotypic hippocampal slice culture model of epileptogenesis

In organotypic hippocampal slice cultures, principal neurons form aberrant excitatory connections with other principal cells in response to slicing-induced deafferentation, similar to mechanisms underlying epileptogenesis in post-traumatic epilepsy. To investigate the consequences of this synaptogen...

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Bibliografiske detaljer
Main Authors: Dyhrfjeld-Johnsen, J., Berdichevsky, Y., Swiercz, W., Sabolek, H., Staley, K.J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167405/
https://ncbi.nlm.nih.gov/pubmed/21076333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNP.0b013e3181fe0709
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