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Interictal spikes, seizures and ictal cell death are not necessary for post-traumatic epileptogenesis in vitro
Clinical studies indicate that phenytoin prevents acute post-traumatic seizures but not subsequent post-traumatic epilepsy. We explored this phenomenon using organotypic hippocampal slice cultures as a model of severe traumatic brain injury. Hippocampal slices were cultured for up to eight weeks, du...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3786688/ https://ncbi.nlm.nih.gov/pubmed/22115940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.11.001 |
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