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Interictal spikes, seizures and ictal cell death are not necessary for post-traumatic epileptogenesis in vitro

Clinical studies indicate that phenytoin prevents acute post-traumatic seizures but not subsequent post-traumatic epilepsy. We explored this phenomenon using organotypic hippocampal slice cultures as a model of severe traumatic brain injury. Hippocampal slices were cultured for up to eight weeks, du...

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Bibliografski detalji
Glavni autori: Berdichevsky, Yevgeny, Dzhala, Volodymyr, Mail, Michelle, Staley, Kevin J.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786688/
https://ncbi.nlm.nih.gov/pubmed/22115940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.11.001
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