Interactions of Phosphatase and Tensin Homologue (PTEN) Proteins with Phosphatidylinositol Phosphates: Insights from Molecular Dynamics Simulations of PTEN and Voltage Sensitive Phosphatase

[Image: see text] The phosphatase and tensin homologue (PTEN) and the Ciona intestinalis voltage sensitive phosphatase (Ci-VSP) are both phosphatidylinositol phosphate (PIP) phosphatases that contain a C2 domain. PTEN is a tumor suppressor protein that acts as a phosphatase on PIP(3) in mammalian ce...

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Detaylı Bibliyografya
Asıl Yazarlar: Kalli, Antreas C., Devaney, Isabel, Sansom, Mark S. P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2014
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167384/
https://ncbi.nlm.nih.gov/pubmed/24588644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5000299
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