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Tau Binds to Lipid Membrane Surfaces via Short Amphipathic Helices Located in Its Microtubule-Binding Repeats

Tau is a microtubule-associated protein that is genetically linked to dementia and linked to Alzheimer’s disease via its presence in intraneuronal neurofibrillary tangle deposits, where it takes the form of aggregated paired helical and straight filaments. Although the precise mechanisms by which ta...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Georgieva, Elka R., Xiao, Shifeng, Borbat, Peter P., Freed, Jack H., Eliezer, David
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Biophysical Society 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167292/
https://ncbi.nlm.nih.gov/pubmed/25229151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.046
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