Cell surface lactate receptor GPR81 is crucial for cancer cell survival

The mechanisms which allow cancer cells to adapt to the typical tumor microenvironment of low oxygen and glucose and high lactate are not well understood. GPR81 is a lactate receptor recently identified in adipose and muscle cells that has not been investigated in cancer. In the current study, we ex...

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Библиографические подробности
Главные авторы: Roland, Christina L., Arumugam, Thiruvengadam, Deng, Defeng, Liu, Shi He, Philip, Bincy, Gomez, Sobeyda, Burns, William R., Ramachandran, Vijaya, Wang, Huamin, Cruz-Monserrate, Zobeida, Logsdon, Craig D.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167222/
https://ncbi.nlm.nih.gov/pubmed/24928781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0319
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