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Cell surface lactate receptor GPR81 is crucial for cancer cell survival

The mechanisms which allow cancer cells to adapt to the typical tumor microenvironment of low oxygen and glucose and high lactate are not well understood. GPR81 is a lactate receptor recently identified in adipose and muscle cells that has not been investigated in cancer. In the current study, we ex...

詳細記述

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書誌詳細
主要な著者: Roland, Christina L., Arumugam, Thiruvengadam, Deng, Defeng, Liu, Shi He, Philip, Bincy, Gomez, Sobeyda, Burns, William R., Ramachandran, Vijaya, Wang, Huamin, Cruz-Monserrate, Zobeida, Logsdon, Craig D.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167222/
https://ncbi.nlm.nih.gov/pubmed/24928781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0319
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