Mitochondrial Targeted Endonuclease III DNA Repair Enzyme Protects against Ventilator Induced Lung Injury in Mice

The mitochondrial targeted DNA repair enzyme, 8-oxoguanine DNA glycosylase 1, was previously reported to protect against mitochondrial DNA (mtDNA) damage and ventilator induced lung injury (VILI). In the present study we determined whether mitochondrial targeted endonuclease III (EndoIII) which clea...

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Main Authors: Hashizume, Masahiro, Mouner, Marc, Chouteau, Joshua M., Gorodnya, Olena M., Ruchko, Mykhaylo V., Wilson, Glenn L., Gillespie, Mark N., Parker, James C.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167202/
https://ncbi.nlm.nih.gov/pubmed/25153040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph7080894
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