High serum levels of Dickkopf-1 are associated with a poor prognosis in prostate cancer patients

BACKGROUND: The Wnt inhibitor Dickkopf-1 (DKK-1) has been linked to the progression of malignant bone disease by impairing osteoblast activity. In addition, there is increasing data to suggest direct tumor promoting effects of DKK-1. The prognostic role of DKK-1 expression in prostate cancer remains...

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Hauptverfasser: Rachner, Tilman D, Thiele, Stefanie, Göbel, Andy, Browne, Andrew, Fuessel, Susanne, Erdmann, Kati, Wirth, Manfred P, Fröhner, Michael, Todenhöfer, Tilman, Muders, Michael H, Kieslinger, Matthias, Rauner, Martina, Hofbauer, Lorenz C
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167148/
https://ncbi.nlm.nih.gov/pubmed/25182503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-649
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