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Human ESC Self-Renewal Promoting microRNAs Induce Epithelial-Mesenchymal Transition in Hepatocytes by Controlling the PTEN and TGFβ Tumor Suppressor Signaling Pathways

The self-renewal capacity ascribed to embryonic stem cells (ESCs) is reminiscent of cancer cell proliferation, raising speculation that a common network of genes may regulate these traits. A search for general regulators of these traits yielded a set of microRNAs for which expression is highly enric...

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Detalhes bibliográficos
Main Authors: Jung, Christine J., Iyengar, Sushma, Blahnik, Kimberly R., Jiang, Joy X., Tahimic, Candice, Torok, Natalie J., de vere White, Ralph W., Farnham, Peggy J., Zern, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166560/
https://ncbi.nlm.nih.gov/pubmed/22622027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0421
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