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Epigenetic Modulation of miR-122 Facilitates Human Embryonic Stem Cell Self-Renewal and Hepatocellular Carcinoma Proliferation

The self-renewal capacity ascribed to hESCs is paralleled in cancer cell proliferation, suggesting that a common network of genes may facilitate the promotion of these traits. However, the molecular mechanisms that are involved in regulating the silencing of these genes as stem cells differentiate i...

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Detalhes bibliográficos
Main Authors: Jung, Christine J., Iyengar, Sushma, Blahnik, Kimberly R., Ajuha, Tijess P., Jiang, Joy X., Farnham, Peggy J., Zern, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225380/
https://ncbi.nlm.nih.gov/pubmed/22140464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027740
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