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Crystal structure of deglycosylated human IgG4-Fc

The Fc region of IgG antibodies, important for effector functions such as antibody-dependent cell-mediated cytotoxicity, antibody-dependent cellular phagocytosis and complement activation, contains an oligosaccharide moiety covalently attached to each C(H)2 domain. The oligosaccharide not only orien...

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Autors principals: Davies, Anna M., Jefferis, Roy, Sutton, Brian J.
Format: Artigo
Idioma:Inglês
Publicat: Pergamon Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166458/
https://ncbi.nlm.nih.gov/pubmed/24956411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2014.05.015
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