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Structural Determinants of Unique Properties of Human IgG4-Fc()
Human IgG4, normally the least abundant of the four subclasses of IgG in serum, displays a number of unique biological properties. It can undergo heavy-chain exchange, also known as Fab-arm exchange, leading to the formation of monovalent but bispecific antibodies, and it interacts poorly with FcγRI...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3905167/ https://ncbi.nlm.nih.gov/pubmed/24211234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.10.039 |
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