Impaired Cav-1 expression in SSc mesenchymal cells upregulates VEGF signaling: a link between vascular involvement and fibrosis

BACKGROUND: Systemic sclerosis (SSc) is characterized by vascular alteration and fibrosis, the former probably leading to fibrosis via the ability of both endothelial cells and pericytes to differentiate toward myofibroblast. It is well known that vascular endothelial growth factor A (VEGF-A, hereaf...

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Autors principals: Cipriani, Paola, Di Benedetto, Paola, Capece, Daria, Zazzeroni, Francesca, Liakouli, Vasiliki, Ruscitti, Piero, Pantano, Ilenia, Berardicurti, Onorina, Carubbi, Francesco, Alesse, Edoardo, Giacomelli, Roberto
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166421/
https://ncbi.nlm.nih.gov/pubmed/25237397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-7-13
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