Impaired Cav-1 expression in SSc mesenchymal cells upregulates VEGF signaling: a link between vascular involvement and fibrosis

BACKGROUND: Systemic sclerosis (SSc) is characterized by vascular alteration and fibrosis, the former probably leading to fibrosis via the ability of both endothelial cells and pericytes to differentiate toward myofibroblast. It is well known that vascular endothelial growth factor A (VEGF-A, hereaf...

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Bibliografiset tiedot
Päätekijät: Cipriani, Paola, Di Benedetto, Paola, Capece, Daria, Zazzeroni, Francesca, Liakouli, Vasiliki, Ruscitti, Piero, Pantano, Ilenia, Berardicurti, Onorina, Carubbi, Francesco, Alesse, Edoardo, Giacomelli, Roberto
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2014
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166421/
https://ncbi.nlm.nih.gov/pubmed/25237397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-7-13
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