Impaired Cav-1 expression in SSc mesenchymal cells upregulates VEGF signaling: a link between vascular involvement and fibrosis

BACKGROUND: Systemic sclerosis (SSc) is characterized by vascular alteration and fibrosis, the former probably leading to fibrosis via the ability of both endothelial cells and pericytes to differentiate toward myofibroblast. It is well known that vascular endothelial growth factor A (VEGF-A, hereaf...

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Detalhes bibliográficos
Main Authors: Cipriani, Paola, Di Benedetto, Paola, Capece, Daria, Zazzeroni, Francesca, Liakouli, Vasiliki, Ruscitti, Piero, Pantano, Ilenia, Berardicurti, Onorina, Carubbi, Francesco, Alesse, Edoardo, Giacomelli, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166421/
https://ncbi.nlm.nih.gov/pubmed/25237397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-7-13
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