Anterograde transport blockade precedes deficits in retrograde transport in the visual projection of the DBA/2J mouse model of glaucoma

Axonal transport deficits have been reported as an early pathology in several neurodegenerative disorders, including glaucoma. However, the progression and mechanisms of these deficits are poorly understood. Previous work suggests that anterograde transport is affected earlier and to a larger degree...

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Dades bibliogràfiques
Autors principals: Dengler-Crish, Christine M., Smith, Matthew A., Inman, Denise M., Wilson, Gina N., Young, Jesse W., Crish, Samuel D.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
Matèries:
Psychiatry
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166356/
https://ncbi.nlm.nih.gov/pubmed/25278826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00290
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