Early Cytoskeletal Protein Modifications Precede Overt Structural Degeneration in the DBA/2J Mouse Model of Glaucoma

Axonal transport deficits precede structural loss in glaucoma and other neurodegenerations. Impairments in structural support, including modified cytoskeletal proteins, and microtubule-destabilizing elements, could be initiating factors in glaucoma pathogenesis. We investigated the time course of ch...

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Bibliografische gegevens
Gepubliceerd in:Front Neurosci
Hoofdauteurs: Wilson, Gina N., Smith, Matthew A., Inman, Denise M., Dengler-Crish, Christine M., Crish, Samuel D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2016
Onderwerpen:
Neuroscience
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093131/
https://ncbi.nlm.nih.gov/pubmed/27857681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00494
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