Anterograde transport blockade precedes deficits in retrograde transport in the visual projection of the DBA/2J mouse model of glaucoma

Axonal transport deficits have been reported as an early pathology in several neurodegenerative disorders, including glaucoma. However, the progression and mechanisms of these deficits are poorly understood. Previous work suggests that anterograde transport is affected earlier and to a larger degree...

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Autores principales: Dengler-Crish, Christine M., Smith, Matthew A., Inman, Denise M., Wilson, Gina N., Young, Jesse W., Crish, Samuel D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2014
Materias:
Psychiatry
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166356/
https://ncbi.nlm.nih.gov/pubmed/25278826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00290
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