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In Vitro and in Vivo Metabolite Profiling of Valnemulin Using Ultraperformance Liquid Chromatography–Quadrupole/Time-of-Flight Hybrid Mass Spectrometry

[Image: see text] Valnemulin, a semisynthetic pleuromutilin derivative related to tiamulin, is broadly used to treat bacterial diseases of animals. Despite its widespread use, metabolism in animals has not yet been fully investigated. To better understand valnemulin biotransformation, in this study,...

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Detalhes bibliográficos
Main Authors: Yang, Shupeng, Shi, Weimin, Hu, Dingfei, Zhang, Suxia, Zhang, Huiyan, Wang, Zhanhui, Cheng, Linli, Sun, Feifei, Shen, Jianzhong, Cao, Xingyuan
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166035/
https://ncbi.nlm.nih.gov/pubmed/25156794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jf5012402
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