Identification of the Metabolic Enzyme Involved Morusin Metabolism and Characterization of Its Metabolites by Ultraperformance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry (UPLC/Q-TOF-MS/MS)

Morusin, the important active component of a traditional Chinese medicine, Morus alba L., has been shown to exhibit many vital pharmacological activities. In this study, six recombinant CYP450 supersomes and liver microsomes were used to perform metabolic studies. Chemical inhibition studies and scr...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Shi, Xianbao, Mackie, Brianna, Zhang, Gang, Yang, Shuman, Song, Yonggui, Su, Dan, Liu, Yali, Shan, Lina
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028857/
https://ncbi.nlm.nih.gov/pubmed/27698677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9240103
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