Fluorescence Detection of KRAS2 mRNA Hybridization in Lung Cancer Cells with PNA-Peptides Containing an Internal Thiazole Orange

[Image: see text] We previously developed reporter-peptide nucleic acid (PNA)-peptides for sequence-specific radioimaging and fluorescence imaging of particular mRNAs in cells and tumors. However, a direct test for PNA-peptide hybridization with RNA in the cytoplasm would be desirable. Thiazole oran...

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Hlavní autoři: Sonar, Mahesh V., Wampole, Matthew E., Jin, Yuan-Yuan, Chen, Chang-Po, Thakur, Mathew L., Wickstrom, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166030/
https://ncbi.nlm.nih.gov/pubmed/25180641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc500304m
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