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Promises and Pitfalls of Intracellular Delivery of Proteins

[Image: see text] The direct delivery of functional proteins into the cell cytosol is a key issue for protein therapy, with many current strategies resulting in endosomal entrapment. Protein delivery to the cytosol is challenging due to the high molecular weight and the polarity of therapeutic prote...

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Detalhes bibliográficos
Main Authors: Fu, Ailing, Tang, Rui, Hardie, Joseph, Farkas, Michelle E., Rotello, Vincent M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166028/
https://ncbi.nlm.nih.gov/pubmed/25133522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc500320j
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