Therapeutic Antitumor Efficacy of B Cells Loaded With Tumor-derived Autophagasomes Vaccine (DRibbles)

Tumor-derived autophagosomes (DRibble) selectively capture tumor-specific antigens and induce a dramatic T-cell activation and expansion when injected into lymph nodes of naive mice. Both dendritic and B cells can efficiently cross-prime antigen-specific T cells. In this report, we demonstrated that...

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Bibliografiske detaljer
Main Authors: Ren, Hongyan, Zhao, Simin, Li, Weixia, Dong, Huixia, Zhou, Meng, Cao, Meng, Hu, Hong-Ming, Wang, Li-xin
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2014
Fag:
Basic Studies
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166015/
https://ncbi.nlm.nih.gov/pubmed/25198526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000051
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