Therapeutic Cancer Vaccination with Immunopeptidomics-Discovered Antigens Confers Protective Antitumor Efficacy

SIMPLE SUMMARY: Immunotherapy has revolutionized cancer treatment, yet many tumors remain resistant to current immuno-oncology therapies. Here we explore a novel, customized oncolytic adenovirus vaccine platform as immunotherapy in a resistant tumor model. We present a workflow for customizing the o...

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Foilsithe in:Cancers (Basel)
Main Authors: Peltonen, Karita, Feola, Sara, Umer, Husen M., Chiaro, Jacopo, Mermelekas, Georgios, Ylösmäki, Erkko, Pesonen, Sari, Branca, Rui M. M., Lehtiö, Janne, Cerullo, Vincenzo
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8306067/
https://ncbi.nlm.nih.gov/pubmed/34298622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143408
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