Tumor-Derived Autophagosome Vaccine: Mechanism of Cross-Presentation and Therapeutic Efficacy

PURPOSE: We previously reported that autophagy in tumor cells plays a critical role in cross-presentation of tumor antigens and that autophagosomes are efficient antigen carriers for cross-priming of tumor-reactive CD8(+) T cells. Here we sought to characterize further the autophagosome-enriched vac...

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Hlavní autoři: Li, Yuhuan, Wang, Li-Xin, Pang, Puiyi, Cui, Zhihua, Aung, Sandra, Haley, Daniel, Fox, Bernard A., Urba, Walter J., Hu, Hong-Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495614/
https://ncbi.nlm.nih.gov/pubmed/22068657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0951
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