PD-1 regulates extrathymic regulatory T-cell differentiation

Regulatory T (Treg) cells and the programmed death-1/programmed death ligand-1 (PD-1/PD-L1) pathway are both critical for maintaining peripheral tolerance to self antigens. A significant subset of Treg cells constitutively expresses PD-1, which prompted an investigation into the role of PD-1/PD-L1 i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chen, Xiufen, Fosco, Dominick, Kline, Douglas E., Meng, Liping, Nishi, Saki, Savage, Peter A., Kline, Justin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165701/
https://ncbi.nlm.nih.gov/pubmed/24975127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344423
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